The method of separating Escherichia coli with a tubular separator:
Escherichia coli, an engineered bacteria, often has such incidental substances in biopharmaceutical production, so the separation of Escherichia coli has become necessary. Today, I recommend a separator - Escherichia coli separator.
The Escherichia coli separator is a mechanical device that uses centrifugal force to separate Escherichia coli and other products in the Escherichia coli mixture.
The Escherichia coli separator is mainly used for high-precision separation; a series of separations are carried out by utilizing the characteristics of different settling speeds of solid particles of different densities or particle sizes in liquids.
The working principle of Escherichia coli separator:
The E. coli mixture was fed to the drum from a feed tube located in the center of the drum. The motor drives a tubular drum to rotate at high speed, and there are no holes on the side of the drum.
The suspension enters from the center of the bottom of the drum. Under the action of centrifugal force, the solid with higher density quickly settles on the inner side of the drum to form a solid layer.
The clarified liquid is drawn upward from the clarified liquid mountain at the central axis of the drum to achieve solid-liquid separation.
The advantages of this E. coli separator are 2:
②The diameter of the rotating drum is small, and it can reach a high speed under the drive of the motor, which can settle very fine worm particles.
The disadvantages of this E. coli separator are:
①The separated solid needs to be stopped and removed manually;
②If there is foam in the suspension, a large number of bubbles will occupy the center of the drum, and the clear liquid will be difficult to draw out, which will affect the separation effect.